The Effects of Pain Controlling Agents on Paediatric Tonsillectomy: A Systematic Review and Network Meta‐Analysis

While ibuprofen appeared to be the most effective in managing postoperative pain, paracetamol showed favourable trends in reducing postoperative bleeding, PONV, and the need for additional analgesics. Ketorolac tended to be associated with a lower incidence of PONV but showed a tendency toward a higher incidence of postoperative bleeding. However, further well-designed, standardised studies would be needed to confirm these conclusions.

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Publication Details

Journal
Clinical Otolaryngology
Published
2025-12-20
DOI
https://doi.org/10.1111/coa.70076
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
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article

The Effects of Pain Controlling Agents on Paediatric Tonsillectomy: A Systematic Review and Network Meta‐Analysis

Clinical Otolaryngology
Inflammatory mediators and NSAID effects
article

The Effects of Pain Controlling Agents on Paediatric Tonsillectomy: A Systematic Review and Network Meta‐Analysis

article en

Abstract

While ibuprofen appeared to be the most effective in managing postoperative pain, paracetamol showed favourable trends in reducing postoperative bleeding, PONV, and the need for additional analgesics. Ketorolac tended to be associated with a lower incidence of PONV but showed a tendency toward a higher incidence of postoperative bleeding. However, further well-designed, standardised studies would be needed to confirm these conclusions.

Clinical OtolaryngologyVol. 51(2)
Duke University (US), St. Mary's Hospital (US), The Catholic University of Korea Bucheon St. Mary's Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR)
Openalex Percentile: Top 56%
Inflammatory mediators and NSAID effects
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