Prognostic factors for recurrence and malignant transformation after treatment of oral epithelial dysplasia: A mixed cohort study

The WHO grading system plays a crucial role in predicting the likelihood of OED recurrence and malignant transformation. Lesion location showed only a non-significant trend, suggesting that its effect may be mediated by grade. These findings highlight the importance of using grading-based risk assessments and ensuring close follow-up care to better manage OED and improve patient outcomes.