Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity

Our findings suggest that CGM metrics, in particular, the simplest metric, CGM mean, was associated with the degree of insulin resistance. Further research is needed to determine whether CGM mean could be a tool to identify normal glucose-tolerant individuals with obesity potentially at risk for progressing to prediabetes and diabetes, and whether its convergence with increased glycemic variability can further contribute to risk prediction of glycemic disorders.

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Publication Details

Journal
Diabetes Care
Published
2025-12-19
DOI
https://doi.org/10.2337/dc25-1395
Primary Topic
Diabetes, Cardiovascular Risks, and Lipoproteins
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity

Diabetes Care
Diabetes, Cardiovascular Risks, and Lipoproteins
article

Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity

article en

Abstract

Our findings suggest that CGM metrics, in particular, the simplest metric, CGM mean, was associated with the degree of insulin resistance. Further research is needed to determine whether CGM mean could be a tool to identify normal glucose-tolerant individuals with obesity potentially at risk for progressing to prediabetes and diabetes, and whether its convergence with increased glycemic variability can further contribute to risk prediction of glycemic disorders.

Diabetes CareVol. 49(1)
University of North Carolina at Chapel Hill (US), The University of Texas at San Antonio Health Science Center (US), Yale University (US), Yale New Haven Health System (US), Texas Diabetes Institute (US), Connecticut Health Foundation (US), Universidade Federal do Espírito Santo (BR)
Openalex Percentile: Top 46%
Diabetes, Cardiovascular Risks, and Lipoproteins
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Association of Insulin Resistance and Insulin Secretion Indices and Glucose Metrics From Continuous Glucose Monitoring in People With Obesity · Diabetes Care (2025) | TGRS Research Map | TGRS