Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results

The foresiGHt trial met its primary efficacy endpoint by demonstrating superiority of lonapegsomatropin vs placebo with similar safety and tolerability, supporting its potential as a once-weekly treatment option for adults with GHD.

Institutions

Publication Details

Journal
The Journal of Clinical Endocrinology & Metabolism
Published
2025-12-19
DOI
https://doi.org/10.1210/clinem/dgaf680
Citations
2
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
Field-Weighted Citation Impact
2.59
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article

Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results

2 citations
The Journal of Clinical Endocrinology & Metabolism
Growth Hormone and Insulin-like Growth Factors
2.59
article

Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results

article en
2 citations

Abstract

The foresiGHt trial met its primary efficacy endpoint by demonstrating superiority of lonapegsomatropin vs placebo with similar safety and tolerability, supporting its potential as a once-weekly treatment option for adults with GHD.

The Journal of Clinical Endocrinology & Metabolism
Jagiellonian University (PL), University of Alicante (ES), Barrow Neurological Institute (US), Mayo Clinic (US), Oregon Health & Science University (US), Washington University in St. Louis (US), WinnMed (US), University of Belgrade (RS), Massachusetts General Hospital (US), Kobe University Hospital (JP), VA Puget Sound Health Care System (US), Hospices Civils de Lyon (FR), Ascendis Pharma (Denmark) (DK), Nara Medical University (JP), Sapienza University of Rome (IT)
Openalex Percentile: Top 8%
Growth Hormone and Insulin-like Growth Factors
2.59
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Efficacy and Safety of Once-Weekly Lonapegsomatropin in Adults With Growth Hormone Deficiency: foresiGHt Trial Results · The Journal of Clinical Endocrinology & Metabolism (2025) | TGRS Research Map | TGRS