Relationship between Indexed Left Atrial Volume and Results of Diastolic Stress Echocardiography in Patients with Preserved Ejection Fraction

Background: The left atrial volume indexed (LAVI) to body surface area, which is also used to measure the left atrium (LA), is a well-known metric that is strongly advised over the LA diameter for evaluating the diastolic function of the left ventricle. In a number of clinical scenarios, it is also a potent prognostic sign. Aim: This study aimed to assess the role of LAVI in detection of elevated LV filling pressure with exercise in comparison with the standard diastolic stress echocardiography in patients with preserved ejection fraction and normal LV filling pressure at rest. Patients and methods: This research is a descriptive cross-sectional study. We looked into 80 patients who had normal resting left ventricular filling pressure but unexplained exertional dyspnea. Exercise may cause higher LV filling pressure in some of these patients. Diastolic stress echocardiography is advised for certain patients according to the most recent guidelines. Every patient had a full resting echocardiogram, which included a resting left atrium volume index to body surface area at rest and an evaluation of diastolic dysfunction using the 2016 recommendations. Following that, we performed diastolic stress echocardiography on each participant and the results were compared to the resting left atrium volume indexed data. Results: Diastolic stress echocardiography results showed that 45% of the study population had positive results, 52.5% had negative results, and 2.5% had inconclusive results. Patients with positive diastolic stress echocardiography had statistically significant higher LA volume index (P value 0.014). Conclusion: Higher LA volume index was linked to patients who had greater e/e~ with exercise, a measure of enhanced LV filling pressure.