Integrative Weaning Index as a Predictor of Successful Weaning from Mechanical Ventilation

Background: Even while mechanical ventilation (MV) is a commonly used supportive treatment among individuals with different types of respiratory failure and has several advantages, it is not a risk-free technique.Aim and objectives: To evaluate the role of the Integrative weaning index (IWI) as a good, considerable, and effective predictor of weaning from mechanical ventilation.Patients and methods: This was a prospective comparative-one blind-single-center study was conducted at Al-Azhar University Hospitals in Cairo, between March 2023 and March 2024, 40 adult patients were among those who underwent more than a 24-hour mechanical ventilation.Results: There was statistically insignificant difference between both groups as regard success rate of weaning (70% vs 60%) with higher successful weaning rate in IWI group 1. IWI at weaning had sensitivity of 91.7% and specificity of 87.5% for predicting weaning success in group 1. At cut off level of 43.5. IWI at weaning had sensitivity of 92.3% and specificity of 71.4% for predicting weaning success in group 2.Conclusion: Our study validates the efficacy of IWI in predicting the result of the weaning process, accurately identifying both successful and unsuccessful outcomes.