Correlation between Visual Field Changes and Structural Measures in Open Angle Glaucoma Patients

Background: Primary open-angle glaucoma (POAG) is a long-lasting, affecting both eyes, a condition characterized by the gradual loss of nerve fibres in the optic nerve, anomalies in the visual field, an open angle in the front chamber of the eye, and increased pressure inside the eye that harms its structure and function. Optic nerve hypoplasia (ONH).Aim of the Work: To evaluate open-angle glaucoma structural and functional alterations with optical coherence tomography (OCT) and visual field perimetry (VF).Patients and Methods: This was a cross-sectional, prospective and observational control study done between May 2023 and November 2023. The venues were the Al-Zahraa University Hospital and Kafr El-Sheikh Eye Hospital. It was done on 70 eyes of 36 cases divided into 2 groups, POAG and control subjects imaged by OCT and (HFA).Results: In the POAG group, A RNFL thickness thinner than control group as mean ± SD by OCT was 74.68 (± 20.33 μm) in POAG, A RNFL thickness mean ± SD by OCT was 92.50 (± 8.88) μm in control and P value in both <0.001, VF median deviation (MD) is 13.07 (± 9.04) in POAG patients and 1.84 (± 1.40 in control group and P value in both <0.001.Conclusion: Optical coherence tomography (OCT) is a crucial diagnostic and monitoring tool for glaucoma. The OCT can reveal structural damage, such as a decrease in retinal nerve fibre layer (RNFL) thickness. This structural damage can be associated with functional impairment, as demonstrated by the Humphrey visual field (HVF) test.