Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study

A higher HGI was associated with increased severity of CKM syndrome. There was a U-shaped relationship between HGI and all-cause mortality while a linear association between HGI and cardiovascular mortality was observed depending on the CKM syndrome stage. HGI may serve as a valuable biomarker for assessing the risk of CKM syndrome and its related mortality.

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Publication Details

Journal
Cardiovascular Diabetology – Endocrinology Reports
Published
2025-12-19
DOI
https://doi.org/10.1186/s40842-025-00262-4
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study

Leiluo Geng, Hongjie Yu, Xue Diao, Aimin Xu
Cardiovascular Diabetology – Endocrinology Reports
Chronic Kidney Disease and Diabetes
article

Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study

Leiluo Geng, Hongjie Yu, Xue Diao, Aimin Xu
article en

Abstract

A higher HGI was associated with increased severity of CKM syndrome. There was a U-shaped relationship between HGI and all-cause mortality while a linear association between HGI and cardiovascular mortality was observed depending on the CKM syndrome stage. HGI may serve as a valuable biomarker for assessing the risk of CKM syndrome and its related mortality.

Cardiovascular Diabetology – Endocrinology ReportsVol. 11(1)
Chinese University of Hong Kong (HK), University of Hong Kong - Shenzhen Hospital (CN), Pharmaceutical Biotechnology (Czechia) (CZ), University of Hong Kong (HK)
National Natural Science Foundation of China, Natural Science Foundation of Guangdong Province
Openalex Percentile: Top 48%
Chronic Kidney Disease and Diabetes
DOIOpen Access PDFOpenAlex
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Association of hemoglobin glycation index with the severity and mortality of cardiovascular-kidney-metabolic syndrome: a population-based cohort study — Leiluo Geng, Hongjie Yu, et al. · Cardiovascular Diabetology – Endocrinology Reports (2025) | TGRS Research Map | TGRS