High-Fat Diet Promotes Tumor Immune Evasion via CD155 Upregulation in Colorectal Cancer
HFD-induced metabolic stress drives immune evasion via the STAT3/CD155 axis. Targeting this pathway may improve ICB efficacy in obesity-related cancers.
Authors
- Jing‐Yuan Fang (ORCID: https://orcid.org/0000-0003-2282-0248)
- Ling Mo
- Guohui Liang
- Liwei Liu (ORCID: https://orcid.org/0000-0002-4133-2816)
- Morris Ling (ORCID: https://orcid.org/0000-0002-9657-8960)
- Yingying Lei
- Zhenzhen Wen (ORCID: https://orcid.org/0009-0000-9604-3520)
- Jingfeng Guo
Institutions
- Sun Yat-sen University (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Immunological Investigations
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1080/08820139.2025.2600597
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00