Potential for gradual tolerance acquisition in egg yolk–induced FPIES: A case series

Early OFC may be conducted at a time that is suboptimal for reliable confirmation of tolerance. A negative OFC result does not necessarily indicate acquisition of full tolerance. Clinicians should be aware of a transitional phase during which symptoms may recur despite initial OFC success. Continued ingestion and close monitoring are essential to confirm full tolerance.

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Publication Details

Journal
Journal of Allergy and Clinical Immunology Global
Published
2025-12-20
DOI
https://doi.org/10.1016/j.jacig.2025.100635
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Potential for gradual tolerance acquisition in egg yolk–induced FPIES: A case series

Tomoaki Kunitsu, Kazuo Nonomura, Kana Hamanaka, Midori Tagaya
Journal of Allergy and Clinical Immunology Global
Food Allergy and Anaphylaxis Research
article

Potential for gradual tolerance acquisition in egg yolk–induced FPIES: A case series

Tomoaki Kunitsu, Kazuo Nonomura, Kana Hamanaka, Midori Tagaya
article en

Abstract

Early OFC may be conducted at a time that is suboptimal for reliable confirmation of tolerance. A negative OFC result does not necessarily indicate acquisition of full tolerance. Clinicians should be aware of a transitional phase during which symptoms may recur despite initial OFC success. Continued ingestion and close monitoring are essential to confirm full tolerance.

Journal of Allergy and Clinical Immunology GlobalVol. 5(2)
Saiseikai Shigaken Hospital (JP)
Openalex Percentile: Top 47%
Food Allergy and Anaphylaxis Research
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