Unveiling the uncommon: A rare case of Sjögren's‐like syndrome in a miniature Schnauzer

Abstract Sjögren's‐like syndrome is a chronic and systemic autoimmune disorder primarily affecting the exocrine glands, leading to symptoms such as xerophthalmia and xerostomia. While Sjögren's‐like syndrome is well‐documented in human medicine, it is rare in veterinary practice, with limited case reports in dogs and cats. This case report describes an 8‐year‐old female miniature Schnauzer diagnosed with Sjögren's‐like syndrome following an initial presentation of seizures, hypersalivation and neck swelling. The dog's history included hypothyroidism and treatment for keratoconjunctivitis sicca. Initial treatment with phenobarbital did not resolve the salivary gland. Following a literature review and ultrasonographic findings, Sjögren's‐like syndrome was diagnosed. Treatment with cyclophosphamide resulted in a reduction in salivary gland swelling. This case underscores the challenges in diagnosing Sjögren's‐like syndrome in veterinary medicine and emphasises the urgent need for increased awareness and research into this rare animal condition.

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Publication Details

Journal
Veterinary Record Case Reports
Published
2025-12-20
DOI
https://doi.org/10.1002/vrc2.70312
Primary Topic
Salivary Gland Disorders and Functions
Type
article
Field-Weighted Citation Impact
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article

Unveiling the uncommon: A rare case of Sjögren's‐like syndrome in a miniature Schnauzer

Evrim Egeden, Lora Koenhemsi̇, Kıvılcım Sönmez, Sinem Yaren Guzelbakan
Veterinary Record Case Reports
Salivary Gland Disorders and Functions
article

Unveiling the uncommon: A rare case of Sjögren's‐like syndrome in a miniature Schnauzer

Evrim Egeden, Lora Koenhemsi̇, Kıvılcım Sönmez, Sinem Yaren Guzelbakan
article en

Abstract

Abstract Sjögren's‐like syndrome is a chronic and systemic autoimmune disorder primarily affecting the exocrine glands, leading to symptoms such as xerophthalmia and xerostomia. While Sjögren's‐like syndrome is well‐documented in human medicine, it is rare in veterinary practice, with limited case reports in dogs and cats. This case report describes an 8‐year‐old female miniature Schnauzer diagnosed with Sjögren's‐like syndrome following an initial presentation of seizures, hypersalivation and neck swelling. The dog's history included hypothyroidism and treatment for keratoconjunctivitis sicca. Initial treatment with phenobarbital did not resolve the salivary gland. Following a literature review and ultrasonographic findings, Sjögren's‐like syndrome was diagnosed. Treatment with cyclophosphamide resulted in a reduction in salivary gland swelling. This case underscores the challenges in diagnosing Sjögren's‐like syndrome in veterinary medicine and emphasises the urgent need for increased awareness and research into this rare animal condition.

Veterinary Record Case ReportsVol. 14(1)
Turkish Society of Hematology (TR), Istanbul University-Cerrahpaşa (TR), Istanbul University (TR)
Openalex Percentile: Top 49%
Salivary Gland Disorders and Functions
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