Association of race and survival in patients treated with apalutamide: Pooled analysis of two phase 3 trials
In this study, the authors did not find any evidence of difference in the treatment effect of apalutamide on OS across patients of different races, although interpretation remains limited by poor representation of racial minorities. Among apalutamide-treated patients, there was no association of race with OS.
Authors
- Eric Jay Small (ORCID: https://orcid.org/0000-0003-3191-6268)
- Yilun Sun (ORCID: https://orcid.org/0000-0002-1341-382X)
- Scott Carlyle Morgan (ORCID: https://orcid.org/0000-0002-6568-3346)
- Shawn Malone (ORCID: https://orcid.org/0000-0001-5497-3455)
- Umang Swami (ORCID: https://orcid.org/0000-0003-3518-0411)
- Zeynep İrem Özay (ORCID: https://orcid.org/0000-0002-4827-9042)
- Georges Gebrael (ORCID: https://orcid.org/0000-0002-4085-6415)
- Angela Y. Jia (ORCID: https://orcid.org/0000-0002-0812-2614)
- Pedro Coelho Barata (ORCID: https://orcid.org/0000-0002-8890-2951)
- Jason Robert Brown (ORCID: https://orcid.org/0000-0001-6225-7555)
- Chadi Hage Chehade (ORCID: https://orcid.org/0009-0008-6735-5777)
- Alicia Katherine Morgans (ORCID: https://orcid.org/0000-0002-6563-4587)
- Daniel Eidelberg Spratt (ORCID: https://orcid.org/0000-0002-5973-4741)
- Amar U. Kishan (ORCID: https://orcid.org/0000-0002-4836-8483)
- Soumyajit Roy (ORCID: https://orcid.org/0000-0001-6617-5522)
- Nicholas George Zaorsky (ORCID: https://orcid.org/0000-0002-4932-1986)
- Iris Yeong- Fung Sheng (ORCID: https://orcid.org/0009-0007-4999-6733)
- Randy Vince (ORCID: https://orcid.org/0000-0002-7779-473X)
- Neal D. Shore (ORCID: https://orcid.org/0000-0001-5767-0548)
- Christopher J. D. Wallis (ORCID: https://orcid.org/0000-0002-5990-4026)
- Neeraj Agarwal (ORCID: https://orcid.org/0000-0003-1076-0428)
- Jorge Alberto Garcia (ORCID: https://orcid.org/0009-0001-6897-4237)
- Fred Saad
- Simon Chowdhury
Institutions
- Mount Sinai Hospital (CA)
- Harvard University (US)
- University of Ottawa (CA)
- University of California, Los Angeles (US)
- Sarah Cannon Research Institute (GB)
- University of California, San Francisco (US)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- University of Utah (US)
- Ottawa Hospital (CA)
- Huntsman Cancer Institute (US)
- Ottawa Regional Cancer Foundation (CA)
- Dana-Farber Cancer Institute (US)
- University Hospitals Seidman Cancer Center (US)
- Centre Hospitalier de l’Université de Montréal (CA)
- Carolina Urologic Research Center (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Cancer
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1002/cncr.70236
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Prostate Cancer Foundation
- University of Toronto