Differences in epiretinal macrophage-like cells and associated retinochoroidal changes between multifocal choroiditis and punctate inner choroidopathy observed using widefield optical coherence tomography angiography

The MFC group demonstrated a significantly greater eMLC density, increased retinochoroidal thickness, and higher density of the choroidal vasculature compared to both the PIC and control groups, between which there were no significant differences. These findings indicate that MFC represents a diffuse, full-thickness retinochoroidal inflammatory process, in contrast to the more localized inflammation characteristic of PIC. Besides, the eMLC may serve as a non-invasive indicator for assessing the severity of fluorescein leakage and retinal inflammation in MFC, offering an objective tool for longitudinal monitoring.