Ultra long-term EEG monitoring for developmental and epileptic encephalopathies: protocol for a prospective study using subscalp EEG
This trial of home monitoring is intended to be of clinical utility to the patient by allowing objective assessment of therapeutic interventions and their effectiveness.Plain language summary.We present a clinical trial protocol for a prospective cohort study in people with severe epilepsies across Italy. The study aims to assess whether an EEG implant placed under the skin (1) is more accurate than patient-reported seizure diary, (2) is feasible and acceptable to patients and clinicians, (3) affect the clinical management of the patients, (4) reduces the impact of epilepsy.
Authors
- Leonilda Bilo
- Paolo Manganotti (ORCID: https://orcid.org/0000-0001-5305-6268)
- Stefano Meletti (ORCID: https://orcid.org/0000-0003-0334-539X)
- Giada Giovannini (ORCID: https://orcid.org/0000-0002-3585-5872)
- Anna Elisabetta Vaudano (ORCID: https://orcid.org/0000-0002-6280-7526)
- Marina Trivisano (ORCID: https://orcid.org/0000-0002-9841-8581)
- Nicola Specchio (ORCID: https://orcid.org/0000-0002-8120-0287)
- Antonietta Coppola (ORCID: https://orcid.org/0000-0002-4845-4293)
- Stefania Maffei (ORCID: https://orcid.org/0000-0002-6428-4300)
- Leonardo Affronte
- Mara Malerba
Institutions
- University of Modena and Reggio Emilia (IT)
- University of Trieste (IT)
- Azienda Ospedaliero-Universitaria di Modena (IT)
- Federico II University Hospital (IT)
- Bambino Gesù Children's Hospital (IT)
Publication Details
- Journal
- Clinical Neurophysiology Practice
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1016/j.cnp.2025.12.005
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00