Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation

MRI-only and CT-MRI fusion-based frameless stereotactic biopsies showed no statistically significant difference in targeting accuracy. While CT-based registration may theoretically reduce distortion-related errors, this was not reflected in our data. The choice of imaging modality should therefore be guided by clinical context and imaging availability. Further prospective studies are needed to clarify the value of CT integration in specific clinical scenarios.

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Publication Details

Journal
Acta Neurochirurgica
Published
2025-12-20
DOI
https://doi.org/10.1007/s00701-025-06720-3
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
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article

Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation

Patrick Dömer, Franziska Meinert, Levent Tanrikulu, Simeon O. A. Helgers et al.
Acta Neurochirurgica
Glioma Diagnosis and Treatment
article

Accuracy of frameless stereotactic brain biopsy: a retrospective cohort study with MRI-only and MRI-CT fusion navigation

Patrick Dömer, Franziska Meinert, Levent Tanrikulu, Simeon O. A. Helgers, Johannes Woitzik, Nikhil Wendt-Thakur
article en

Abstract

MRI-only and CT-MRI fusion-based frameless stereotactic biopsies showed no statistically significant difference in targeting accuracy. While CT-based registration may theoretically reduce distortion-related errors, this was not reflected in our data. The choice of imaging modality should therefore be guided by clinical context and imaging availability. Further prospective studies are needed to clarify the value of CT integration in specific clinical scenarios.

Acta NeurochirurgicaVol. 167(1)
Carl von Ossietzky Universität Oldenburg (DE), Evangelisches Krankenhaus Oldenburg (DE), Friedrich Schiller University Jena (DE)
Openalex Percentile: Top 38%
Glioma Diagnosis and Treatment
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