Short-Term Clinical Outcomes of Platelet-Rich Plasma Therapy in Patellofemoral Chondromalacia: Evaluating Pain Reduction and Functional Improvement in a Six-Month Retrospective Study

PRP injections were associated with a significant reduction in pain and improvement in knee function in patients with patellofemoral chondromalacia, particularly in middle-aged and older populations. Despite significant symptomatic relief, no structural changes in cartilage were observed over six months, as the Outerbridge grade remained unchanged in all patients (mean 2.30±0.79 before and after treatment; p=1.000). These findings support further investigation into the use of PRP as a non-surgical treatment option, warranting additional research to assess its long-term effects and comparative efficacy.