Behind the COVID-19 Curtain: A Rare Case of Autochthonous Pneumonic Tularemia in Portugal

The presence of <i>Francisella tularensis</i> has been well documented in Portugal; however, reports of human infection remain rare. We report the case of a 63-year-old woman presenting with pneumonia and SARS-CoV-2 infection. The relapsing course of infection, partial response to fluoroquinolone and macrolide antibiotics, and epidemiological background led to the suspicion of an underlying zoonotic disease. Serology later confirmed <i>F. tularensis</i> infection, and the patient improved under directed therapy. To the best of our knowledge, this is the first case of autochthonous pneumonic tularemia reported in Portugal.

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Publication Details

Journal
Cureus
Published
2025-12-20
DOI
https://doi.org/10.7759/cureus.99693
Primary Topic
Bacillus and Francisella bacterial research
Type
article
Field-Weighted Citation Impact
0.00
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article

Behind the COVID-19 Curtain: A Rare Case of Autochthonous Pneumonic Tularemia in Portugal

João Rua, David Sousa, Cláudia N. Paiva, João Pina Cabral
Cureus
Bacillus and Francisella bacterial research
article

Behind the COVID-19 Curtain: A Rare Case of Autochthonous Pneumonic Tularemia in Portugal

João Rua, David Sousa, Cláudia N. Paiva, João Pina Cabral
article en

Abstract

The presence of <i>Francisella tularensis</i> has been well documented in Portugal; however, reports of human infection remain rare. We report the case of a 63-year-old woman presenting with pneumonia and SARS-CoV-2 infection. The relapsing course of infection, partial response to fluoroquinolone and macrolide antibiotics, and epidemiological background led to the suspicion of an underlying zoonotic disease. Serology later confirmed <i>F. tularensis</i> infection, and the patient improved under directed therapy. To the best of our knowledge, this is the first case of autochthonous pneumonic tularemia reported in Portugal.

CureusVol. 17(12)
Escola Superior de Tecnologia da Saúde de Coimbra (PT)
Openalex Percentile: Top 62%
Bacillus and Francisella bacterial research
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Behind the COVID-19 Curtain: A Rare Case of Autochthonous Pneumonic Tularemia in Portugal — João Rua, David Sousa, et al. · Cureus (2025) | TGRS Research Map | TGRS