Electrochemical <i>meta</i> -C–H Silylation of Pyridines with Hydrosilanes
An electrochemical <i>meta</i>-C-H silylation of pyridines with readily available hydrosilanes is described. The reaction proceeds under mild conditions without noble metal catalysts or external oxidants using <i>N</i>-hydroxyphthalimide as a hydrogen-atom-transfer catalyst. In addition, quinolines and pyrazines are well tolerated, affording the corresponding silyl-functionalized azines.
Authors
- De‐Yong Yang
- Feng Zhou (ORCID: https://orcid.org/0000-0002-6729-1311)
- Shengchao Yang (ORCID: https://orcid.org/0000-0002-8806-5305)
- Pengwei Xu (ORCID: https://orcid.org/0000-0002-9653-8328)
- Zheng Zhang (ORCID: https://orcid.org/0009-0003-4021-9349)
- Ziyi Wang (ORCID: https://orcid.org/0000-0001-9055-6798)
- Jian Zhou (ORCID: https://orcid.org/0000-0003-0679-6735)
Institutions
- Shihezi University (CN)
- Ministry of Education of the People's Republic of China (CN)
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Organic Chemistry (CN)
- Silicon Chemical (United States) (US)
- Green Chemistry (PL)
- State Key Laboratory of Organometallic Chemistry
- East China Normal University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1021/acs.joc.5c02473
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00