Early skeletal muscle loss and clinical outcomes in critically ill patients in the medical intensive care unit: A retrospective cohort study

More than half of the patients in the ICU experienced significant muscle loss within the first week of being admitted. Receiving structured rehabilitation at Level 3 or higher was independently associated with reduced muscle wasting. This suggests that early mobilization strategies may help preserve muscle mass in critically ill patients.

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Journal
PLoS ONE
Published
2025-12-18
DOI
https://doi.org/10.1371/journal.pone.0338315
Primary Topic
Intensive Care Unit Cognitive Disorders
Type
article
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article

Early skeletal muscle loss and clinical outcomes in critically ill patients in the medical intensive care unit: A retrospective cohort study

Song‐I Lee, Da Hyun Kang, Mi Ra Lee, So Young Ahn et al.
PLoS ONE
Intensive Care Unit Cognitive Disorders
article

Early skeletal muscle loss and clinical outcomes in critically ill patients in the medical intensive care unit: A retrospective cohort study

Song‐I Lee, Da Hyun Kang, Mi Ra Lee, So Young Ahn, D.K. Kim, So-Yun Kim
article en

Abstract

More than half of the patients in the ICU experienced significant muscle loss within the first week of being admitted. Receiving structured rehabilitation at Level 3 or higher was independently associated with reduced muscle wasting. This suggests that early mobilization strategies may help preserve muscle mass in critically ill patients.

PLoS ONEVol. 20(12)
Chungnam National University Hospital (KR), National Institute for Mathematical Sciences (KR)
Openalex Percentile: Top 50%
Intensive Care Unit Cognitive Disorders
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