The risks and benefits of disseminated intravascular coagulation-targeted anticoagulant therapy in abdominal sepsis
DIC-targeted anticoagulant therapy in patients with abdominal sepsis was related with improved prognosis but increased bleeding risks. The risk-benefit profile varies with disease severity, suggesting a need for cautious and personalized treatment strategies.
Authors
- Tadashi Matsuoka (ORCID: https://orcid.org/0000-0002-3837-8960)
- Ryo Hisamune (ORCID: https://orcid.org/0009-0009-3339-1902)
- Noritaka Ushio (ORCID: https://orcid.org/0000-0001-7807-7428)
- Kazuma Yamakawa (ORCID: https://orcid.org/0000-0003-2999-4021)
- Junichi Sasaki (ORCID: https://orcid.org/0000-0002-5190-8524)
- Koichiro Homma (ORCID: https://orcid.org/0000-0001-5223-9599)
Institutions
- Keio University (JP)
- Osaka University of Pharmaceutical Sciences (JP)
Publication Details
- Journal
- Thrombosis Research
- Published
- 2025-12-11
- DOI
- https://doi.org/10.1016/j.thromres.2025.109562
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00