Exercise alveolar oxygen extraction rate reflects ventilatory efficiency and predicts outcomes in idiopathic pulmonary fibrosis
These results show that ∆F<sub>O2</sub> at peak exercise, which is correlated with ventilatory efficiency related to carbon dioxide clearance, is independent of ventilatory ability and is a stronger prognostic factor for survival than physiological ventilatory impairments with hypoxemia in IPF. CPET is essential for evaluating exercise alveolar O<sub>2</sub> extraction and guiding the optimal management of patients with IPF.
Authors
- Ryosuke Nishijima
- Kazuhiko Sugisawa
- Hiroshi Kida (ORCID: https://orcid.org/0000-0002-9351-7855)
- Keisuke Miki (ORCID: https://orcid.org/0000-0002-3600-8595)
- T. Matsuki (ORCID: https://orcid.org/0000-0002-4416-6083)
- Yasuhiro Mihashi
- Yuka Nagata
- Kazuyuki Tsujino
- Takuro Nii
Institutions
- Toneyama National Hospital (JP)
Publication Details
- Journal
- BMC Pulmonary Medicine
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1186/s12890-025-04064-3
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00