Exploring Immune Mechanisms in Leprosy: The Role of Serum Interleukin-17 and Tumor Necrosis Factor-alpha in the Immunopathogenesis of the Disease in Sudanese Patients
Cytokine dysregulation, particularly reduced IL-17 and elevated TNF-α, reflects distinct immune pathways in leprosy pathogenesis. These biomarkers may aid in assessing disease activity and treatment response.
Authors
- Nahid Mahmoud Hassan Elamin (ORCID: https://orcid.org/0000-0003-1868-2284)
- Mohammed Helmy Faris Shalayel (ORCID: https://orcid.org/0000-0002-6968-8048)
- Mashael Hakami (ORCID: https://orcid.org/0000-0001-7037-9333)
- Aline Sayd
- Aamir Abdullahi Hamzza
- S. Khalil (ORCID: https://orcid.org/0000-0002-4431-8921)
- Hassan Gumaa Mustafa Hamid
- Abdullah M. Qahl
- Amar Babikir Elhussein (ORCID: https://orcid.org/0000-0002-5509-066X)
- Husham E. Homeida
- Soad Mohammed Alfadol
- Muhammad Moaaz Ali (ORCID: https://orcid.org/0000-0002-3092-6328)
- Ogail Yousif Dawod (ORCID: https://orcid.org/0000-0002-4439-0173)
- Omar E. Fadlelseed
- A. Ahmed
- Faisal Hakami
- Rahika Ibrahim Zeleei
- Fadia Abdalla Saeed Khairi
Institutions
- University of Khartoum (SD)
- Nile Valley University (SD)
- Alzaiem Alazhari University (SD)
- Ministry of Higher Education And Scientific Research (SD)
- University of Hafr Al-Batin (SA)
- University of Bahri (SD)
- King Abdullah Medical City (SA)
- Najran University (SA)
- Jazan University (SA)
Publication Details
- Journal
- International Journal of Mycobacteriology
- Published
- 2025-10-01
- DOI
- https://doi.org/10.4103/ijmy.ijmy_197_25
- Primary Topic
- Leprosy Research and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00