A case of rectal MiNEN demonstrating vascular stalk-like imaging and gross demarcation of tumor components

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the rectum are extremely rare and pose significant diagnostic challenges. We report a 69-year-old man with rectal MiNEN successfully treated with a robot-assisted Hartmann's procedure. Preoperative contrast-enhanced CT revealed a vascular stalk-like structure within the tumor. Gross pathology showed a clear demarcation between adenocarcinoma and small-cell neuroendocrine carcinoma. Robot-assisted surgery facilitated precise dissection in the narrow pelvic cavity and safe distal transection through a transanal approach. This case highlights unique radiological and pathological findings that may aid in the diagnosis and management of rectal MiNEN.

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Publication Details

Journal
Journal of Surgical Case Reports
Published
2025-11-29
DOI
https://doi.org/10.1093/jscr/rjaf996
Primary Topic
Neuroendocrine Tumor Research Advances
Type
article
Field-Weighted Citation Impact
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article

A case of rectal MiNEN demonstrating vascular stalk-like imaging and gross demarcation of tumor components

Kazuki Kato, Koichiro Sawada, Daisuke Fujimori, Noriyuki Inaki et al.
Journal of Surgical Case Reports
Neuroendocrine Tumor Research Advances
article

A case of rectal MiNEN demonstrating vascular stalk-like imaging and gross demarcation of tumor components

Kazuki Kato, Koichiro Sawada, Daisuke Fujimori, Noriyuki Inaki, Masato Hayashi, Masanori Kotake, Munenori Mukai, Takuo Hara, Hironori Hayashi, Takahiro Yoshimura, H. Kitabayashi, Kenichiro Tsukada, Kaeko Oyama
article en

Abstract

Mixed neuroendocrine-non-neuroendocrine neoplasms (MiNENs) of the rectum are extremely rare and pose significant diagnostic challenges. We report a 69-year-old man with rectal MiNEN successfully treated with a robot-assisted Hartmann's procedure. Preoperative contrast-enhanced CT revealed a vascular stalk-like structure within the tumor. Gross pathology showed a clear demarcation between adenocarcinoma and small-cell neuroendocrine carcinoma. Robot-assisted surgery facilitated precise dissection in the narrow pelvic cavity and safe distal transection through a transanal approach. This case highlights unique radiological and pathological findings that may aid in the diagnosis and management of rectal MiNEN.

Journal of Surgical Case ReportsVol. 2025(12)
Kanazawa University (JP), Kanazawa Medical University (JP), Kouseiren Takaoka Hospital (JP)
Openalex Percentile: Top 47%
Neuroendocrine Tumor Research Advances
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