Efficacy and safety of stem cell therapy in patients with chronic lower extremity ulcers: an umbrella review of systematic reviews and meta-analyses
SCT represents a promising adjunctive therapy for CLEUs, with many studies demonstrating its safety and potential benefits. Since current evidence is limited by methodological flaws and study heterogeneity, high-quality RCTs in the future are crucial to prove the benefits of SCT for CLEUs truly.
Authors
- Yi Cao (ORCID: https://orcid.org/0000-0002-5087-8861)
- Zheng Lin (ORCID: https://orcid.org/0000-0001-5242-716X)
- Qiu-Shuang Li
- H. Wang (ORCID: https://orcid.org/0009-0001-8950-6061)
- Caihong Ma (ORCID: https://orcid.org/0000-0003-0439-9621)
- Shan Liu (ORCID: https://orcid.org/0000-0002-8159-2778)
Institutions
- Zhejiang Chinese Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1186/s13287-025-04853-x
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00