miRquad: first-in-class dPCR multiplex TaqMan™ Advanced clinical research assay for microRNA detection in head and neck cancer
The assay overcomes common challenges associated with multiple miRNAs detection, particularly in liquid biopsy samples (e.g., multiple pipetting issues, increased consumption of sample for multiple assessment, extended TAT for complete profiling) and provides robust and accurate detection, demonstrating potential for real-time patient monitoring and prognostication in HNC.
Authors
- Stella Gagliardi (ORCID: https://orcid.org/0000-0002-6589-6907)
- Eloisa Arbustini (ORCID: https://orcid.org/0000-0003-2948-7994)
- Stefano Ferrero (ORCID: https://orcid.org/0000-0002-3715-0737)
- Federica Ganci (ORCID: https://orcid.org/0000-0002-8010-2183)
- Roberta Maestro (ORCID: https://orcid.org/0000-0002-6642-5592)
- Antonio Pisani (ORCID: https://orcid.org/0000-0002-8432-594X)
- Matteo Allegretti (ORCID: https://orcid.org/0000-0003-3398-8775)
- David Joun
- Junko Stevens
- Alfredo Budillon (ORCID: https://orcid.org/0000-0002-6330-6053)
- Valentina De Pascale (ORCID: https://orcid.org/0000-0003-1015-8867)
- Simona De Summa (ORCID: https://orcid.org/0000-0001-9607-3754)
- Tania Moccia (ORCID: https://orcid.org/0000-0002-0463-9552)
- Giovanni Blandino (ORCID: https://orcid.org/0000-0002-6970-2241)
- Luca Sigalotti (ORCID: https://orcid.org/0000-0002-1436-2358)
- Elena Di Gennaro (ORCID: https://orcid.org/0000-0001-6223-7845)
- Amalia Azzariti (ORCID: https://orcid.org/0000-0002-6149-5049)
- Gennaro Ciliberto (ORCID: https://orcid.org/0000-0003-2851-8605)
- Paola C. Muti (ORCID: https://orcid.org/0000-0003-0339-8520)
- Chiara Ciardiello (ORCID: https://orcid.org/0000-0003-2042-8672)
- Giada Anna Beltramini (ORCID: https://orcid.org/0000-0002-4351-0276)
- Mario Urtis (ORCID: https://orcid.org/0000-0003-3289-9228)
- Raul Pellini (ORCID: https://orcid.org/0000-0001-6051-3041)
- G Urbani (ORCID: https://orcid.org/0009-0009-1343-3415)
- Stefano Fiori
Institutions
- University of Milan (IT)
- University of Pavia (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Centro di Riferimento Oncologico (IT)
- Istituto Tumori Bari (IT)
- National Cancer Institute (MY)
- Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" (IT)
- Thermo Fisher Scientific (United States) (US)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Journal of Experimental & Clinical Cancer Research
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1186/s13046-025-03590-6
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00