PLAAT2 facilitates the development of pancreatic cancer and serves as a predictor of resistance to chemotherapy
Collectively, these data support an oncogenic role of PLAAT2 in PC and indicate that PLAAT2 and its associated transcriptional signature may serve as potential biomarkers of prognosis and chemotherapeutic response, as well as candidate targets for precision therapy in PC.
Authors
- Jingjing Lu (ORCID: https://orcid.org/0000-0003-3831-5537)
- Ting Liang (ORCID: https://orcid.org/0000-0003-4121-0787)
- Jian Wan (ORCID: https://orcid.org/0000-0001-5904-9261)
- Qingsong Guo (ORCID: https://orcid.org/0000-0001-5194-2370)
- Chun‐Te Wu (ORCID: https://orcid.org/0000-0002-6910-9253)
- Yuhua Lu (ORCID: https://orcid.org/0000-0002-9563-4844)
- Xiaohong Li (ORCID: https://orcid.org/0000-0003-0336-7302)
- Qiyang Chen
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1186/s12885-025-15481-2
- Primary Topic
- Genomics and Chromatin Dynamics
- Type
- article
- Field-Weighted Citation Impact
- 0.00