Proteomic and Molecular Analysis of Viable Bone Debris From Foot and Ankle Osteotomies: Implications for Autologous Grafting

The results could serve as a foundation for repurposing previously discarded bone debris as autologous bone grafts for reimplantation in minimally invasive orthopaedic procedures to potentially enhance bone tissue healing. To confirm clinical relevance, further well-controlled trials are required to establish whether these findings improve bone healing rates and related patient-reported outcomes.

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Publication Details

Journal
Foot & Ankle Orthopaedics
Published
2025-10-01
DOI
https://doi.org/10.1177/24730114251398510
Primary Topic
Periodontal Regeneration and Treatments
Type
article
Field-Weighted Citation Impact
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article

Proteomic and Molecular Analysis of Viable Bone Debris From Foot and Ankle Osteotomies: Implications for Autologous Grafting

Thomas Michael Best, Steven D. Steinlauf, Noah Gabor, Dimitrios Kouroupis et al.
Foot & Ankle Orthopaedics
Periodontal Regeneration and Treatments
article

Proteomic and Molecular Analysis of Viable Bone Debris From Foot and Ankle Osteotomies: Implications for Autologous Grafting

Thomas Michael Best, Steven D. Steinlauf, Noah Gabor, Dimitrios Kouroupis, Kevin Liebmann, Kirin Cromer
article en

Abstract

The results could serve as a foundation for repurposing previously discarded bone debris as autologous bone grafts for reimplantation in minimally invasive orthopaedic procedures to potentially enhance bone tissue healing. To confirm clinical relevance, further well-controlled trials are required to establish whether these findings improve bone healing rates and related patient-reported outcomes.

Foot & Ankle OrthopaedicsVol. 10(4)
University of Miami Health System (US), Stem Cell Institute (PA), Miami Transplant Institute (US)
Openalex Percentile: Top 43%
Periodontal Regeneration and Treatments
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