Association between vitamins intake and kidney stone: A cross-sectional study

The present study aimed to evaluate the relationships between dietary intake of vitamins and kidney stone (KS) prevalence among US adults. A total of 5721 participants from the National Health and Nutrition Examination Survey were included. Logistic regression models were utilized to examine the associations between vitamin A, C, D, E intake and KS. We found that vitamin C and vitamin E were negatively associated with KS, vitamin D was positively associated with KS. Compared to T1 (the lowest tertile), the odds ratios (ORs) and 95% confidence intervals (CIs) for vitamin C were 0.92 (0.79-0.95) for T2 and 0.86 (0.73-0.95) for T3 (P trend < .01). With regard to vitamin D, ORs and 95% CIs were 1.05 (1.01-1.22) and 1.10 (1.02-1.35) for T2 and T3, respectively (P trend < .01). With regard to vitamin E, ORs and 95% CIs were 0.93 (0.81-0.95) and 0.82 (0.70-0.90) for T2 and T3, respectively (P trend < .01). The associations between vitamins and KS were similar among subgroup analysis. The study shows that more intake of vitamin C and E may be associated with a lower prevalence of KS, whereas increased intake of vitamin D may be linked to a higher prevalence.