Zinc pyrithione impairs iron-sulfur cluster biogenesis in Mycobacterium tuberculosis

ZnPT exhibits antimycobacterial activity by disrupting Fe-S cluster biogenesis and impairing energy metabolism in Mtb.

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Publication Details

Journal
BMC Microbiology
Published
2025-12-20
DOI
https://doi.org/10.1186/s12866-025-04644-7
Primary Topic
Metalloenzymes and iron-sulfur proteins
Type
article
Field-Weighted Citation Impact
0.00
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article

Zinc pyrithione impairs iron-sulfur cluster biogenesis in Mycobacterium tuberculosis

Lu Wang, Bin Wang, Xuelin Wang, Lu Yu et al.
BMC Microbiology
Metalloenzymes and iron-sulfur proteins
article

Zinc pyrithione impairs iron-sulfur cluster biogenesis in Mycobacterium tuberculosis

Lu Wang, Bin Wang, Xuelin Wang, Lu Yu, Yun Ye, Ji De, Lingling Xu
article en

Abstract

ZnPT exhibits antimycobacterial activity by disrupting Fe-S cluster biogenesis and impairing energy metabolism in Mtb.

BMC MicrobiologyVol. 26(1)
Capital Medical University (CN), Beijing Chest Hospital (CN)
Openalex Percentile: Top 69%
Metalloenzymes and iron-sulfur proteins
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