Treatment with tumor necrosis factor inhibitors during pregnancy and occurrence of severe infections among exposed infants in Germany
Our analyses showed that among children whose mothers used TNFi in the year before or during pregnancy, about one fourth was exposed to TNFi in the second half of pregnancy. Among these children, the proportion hospitalized with a severe infection in the first year of life was similar to that from mothers exposed only before pregnancy.
Authors
- Ulrike Haug (ORCID: https://orcid.org/0000-0002-1886-2923)
- Kathrin Thöne (ORCID: https://orcid.org/0000-0002-3114-8273)
- Christina Princk (ORCID: https://orcid.org/0000-0001-9265-8480)
- Bianca Kollhorst (ORCID: https://orcid.org/0000-0001-5964-954X)
- Marlies Onken (ORCID: https://orcid.org/0000-0002-4385-612X)
- Nadine Wentzell (ORCID: https://orcid.org/0000-0002-2983-0222)
Institutions
- Humboldt-Universität zu Berlin (DE)
- Techniker Krankenkasse (Germany) (DE)
- Leibniz Institute for Prevention Research and Epidemiology - BIPS (DE)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1186/s12884-025-08590-0
- Primary Topic
- Pregnancy and Medication Impact
- Type
- article
- Field-Weighted Citation Impact
- 0.00