Increased choroidal stromal volume and altered choriocapillaris perfusion in neovascular AMD: An SS-OCTA association study
This cross-sectional study demonstrated an association between increased CSV and the presence of nAMD, including in high-risk fellow eyes. The inverse correlation between CSV and CCFD in nAMD eyes suggested a potential interplay between stromal expansion and microvascular compromise. These findings highlighted increased CSV as a candidate biomarker that warranted investigation in future longitudinal studies to determine its prognostic value for nAMD development.
Authors
- Miaoling Li
- Feng Wen (ORCID: https://orcid.org/0000-0003-3319-4051)
- Xinlei Hao (ORCID: https://orcid.org/0000-0001-8322-0989)
- Xiongze Zhang (ORCID: https://orcid.org/0000-0001-5530-4202)
- Yining Zhang (ORCID: https://orcid.org/0000-0002-3153-8407)
- Yuying Ji (ORCID: https://orcid.org/0000-0001-5249-9200)
- Jiaxin Pu
- Xuelin Chen (ORCID: https://orcid.org/0000-0002-8572-9989)
- Xuenan Zhuang (ORCID: https://orcid.org/0000-0003-0611-452X)
- Guiqin He
Institutions
- Sun Yat-sen University (CN)
- Guangdong Academy of Medical Sciences (CN)
Publication Details
- Journal
- Photodiagnosis and Photodynamic Therapy
- Published
- 2025-12-20
- DOI
- https://doi.org/10.1016/j.pdpdt.2025.105327
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00