A Rare Case of Coexisting Medullary and Papillary Thyroid Carcinomas With Parathyroid Adenoma in Pancreatic Neuroendocrine Tumour (pNET)

We present a rare and complex case involving the simultaneous occurrence of medullary thyroid carcinoma (MTC), papillary thyroid carcinoma (PTC), and a parathyroid adenoma in a 79-year-old male. Additionally, incidental radiological findings suggest a pancreatic neuroendocrine tumour (NET). The coexistence of these diverse endocrine disorders is exceptionally uncommon and raises important questions regarding potential syndromic associations. Such cases highlight the necessity for thorough diagnostic evaluation, individualised treatment planning, and the collaboration of a multidisciplinary team, including endocrinologists, oncologists, surgeons, radiologists, and pathologists, to ensure optimal patient outcomes.

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Publication Details

Journal
Cureus
Published
2025-12-19
DOI
https://doi.org/10.7759/cureus.99654
Primary Topic
Thyroid Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A Rare Case of Coexisting Medullary and Papillary Thyroid Carcinomas With Parathyroid Adenoma in Pancreatic Neuroendocrine Tumour (pNET)

Sunil Zachariah, Nazia Binte Salam, Fahmida Tithi
Cureus
Thyroid Cancer Diagnosis and Treatment
article

A Rare Case of Coexisting Medullary and Papillary Thyroid Carcinomas With Parathyroid Adenoma in Pancreatic Neuroendocrine Tumour (pNET)

Sunil Zachariah, Nazia Binte Salam, Fahmida Tithi
article en

Abstract

We present a rare and complex case involving the simultaneous occurrence of medullary thyroid carcinoma (MTC), papillary thyroid carcinoma (PTC), and a parathyroid adenoma in a 79-year-old male. Additionally, incidental radiological findings suggest a pancreatic neuroendocrine tumour (NET). The coexistence of these diverse endocrine disorders is exceptionally uncommon and raises important questions regarding potential syndromic associations. Such cases highlight the necessity for thorough diagnostic evaluation, individualised treatment planning, and the collaboration of a multidisciplinary team, including endocrinologists, oncologists, surgeons, radiologists, and pathologists, to ensure optimal patient outcomes.

CureusVol. 17(12)
East Surrey Hospital (GB)
Openalex Percentile: Top 46%
Thyroid Cancer Diagnosis and Treatment
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