Hotspots and frontiers of the relationship between hepatocellular carcinoma and cancer-associated fibroblasts: a bibliometric analysis and review
CAFs research in HCC has transitioned from descriptive studies to precision therapeutic targeting. Future directions involve dissecting CAFs plasticity, leveraging single-cell multiomics, and optimizing combination therapies to overcome TME-mediated resistance.
Authors
- Xingxing Hu (ORCID: https://orcid.org/0000-0001-6385-4845)
- Guanglan Chen
- Lingling Ren
- Huixia Zheng
Institutions
- Lishui City People's Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1007/s12672-025-04245-w
- Primary Topic
- Cancer Cells and Metastasis
- Type
- article
- Field-Weighted Citation Impact
- 0.00