Depression and weight loss trajectories during an integrated behavioral intervention: Within-treatment analysis of the RAINBOW trial

We identified three joint trajectories of depression symptom scores and obesity. Members in the three trajectories saw varying degrees of symptom reduction from baseline to 12 months. Results suggest adaptive treatment trials may be needed for participants in groups with lower anticipated depression symptom scores and/or weight reductions.

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Journal
PLoS ONE
Published
2025-12-19
DOI
https://doi.org/10.1371/journal.pone.0328715
Primary Topic
Bariatric Surgery and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Depression and weight loss trajectories during an integrated behavioral intervention: Within-treatment analysis of the RAINBOW trial

Daphne Lew, Thomas Kannampallil, Nan Lv, Jun Ma et al.
PLoS ONE
Bariatric Surgery and Outcomes
article

Depression and weight loss trajectories during an integrated behavioral intervention: Within-treatment analysis of the RAINBOW trial

Daphne Lew, Thomas Kannampallil, Nan Lv, Jun Ma, Bailey W. Osweiler
article en

Abstract

We identified three joint trajectories of depression symptom scores and obesity. Members in the three trajectories saw varying degrees of symptom reduction from baseline to 12 months. Results suggest adaptive treatment trials may be needed for participants in groups with lower anticipated depression symptom scores and/or weight reductions.

PLoS ONEVol. 20(12)
Chicago Department of Public Health (US), Washington University in St. Louis (US), University of Illinois Chicago (US)
Openalex Percentile: Top 39%
Bariatric Surgery and Outcomes
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Depression and weight loss trajectories during an integrated behavioral intervention: Within-treatment analysis of the RAINBOW trial — Daphne Lew, Thomas Kannampallil, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS