Evidence for loss of contractile phenotype of the mouse aortic vascular smooth muscle (MOVAS) cell line with increasing number of passages in vitro
MOVAS cells undergo a transition from contractile to synthetic phenotype with increasing number of passages in vitro, which means that these cells should be used with caution, at a low number of passages, while being regularly characterized.
Authors
- Stéphane Jaisson (ORCID: https://orcid.org/0000-0002-8491-6563)
- Anaïs Okwieka (ORCID: https://orcid.org/0000-0002-8945-664X)
- Christine Piètrement (ORCID: https://orcid.org/0000-0002-3234-5105)
- Alexandre Berquand (ORCID: https://orcid.org/0000-0002-3863-8048)
- Philippe Gillery (ORCID: https://orcid.org/0000-0002-1100-8759)
- Lucile Cadoret
Institutions
- Centre National de la Recherche Scientifique (FR)
- Centre Hospitalier Universitaire de Reims (FR)
- Université de Reims Champagne-Ardenne (FR)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1371/journal.pone.0339118
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centre National de la Recherche Scientifique