Fecal microbiota composition and function are associated with anxiety and depression in patients with inflammatory bowel disease
In this study, the alteration of composition of fecal microbiota was identified, and differential genus associated with IBD patients with anxiety or depression or both were explored. Change in function of microbiota was also discovered by the detection of differential pathways and fecal metabolites, which were associated with IBD patients with anxiety or depression or both.
Authors
- Jing Wu (ORCID: https://orcid.org/0000-0003-3009-4434)
- Yan Dang (ORCID: https://orcid.org/0000-0002-8326-9763)
- Peng Li (ORCID: https://orcid.org/0000-0002-2533-1864)
- Shutian Zhang (ORCID: https://orcid.org/0000-0003-2356-4397)
- Chenyue Xu (ORCID: https://orcid.org/0000-0002-8484-3181)
- Minsi Zhou (ORCID: https://orcid.org/0000-0001-8913-4109)
- Haiyun Shi (ORCID: https://orcid.org/0000-0001-5793-1138)
- Xinyi Xu (ORCID: https://orcid.org/0009-0007-5357-4111)
- Fang Xu (ORCID: https://orcid.org/0009-0001-5703-0812)
- Xueping Huang (ORCID: https://orcid.org/0000-0003-2803-2277)
- Zhan Wang (ORCID: https://orcid.org/0009-0000-6968-7638)
Institutions
- National Clinical Research Center for Digestive Diseases (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1371/journal.pone.0337941
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.00