Association of LINE-1 RNA expressions in cell lines with longevity and reproductive lifespan
These results from a small cohort of research subjects lend support to the hypothesis that the regulation of L1 RNA expressions in adults significantly influences the rates of both systemic and reproductive aging. Expanded studies of similar design are needed to further test this hypothesis.
Authors
- Ken R. Smith (ORCID: https://orcid.org/0000-0003-0682-3705)
- Richard Cawthon (ORCID: https://orcid.org/0000-0001-6073-9112)
Institutions
- University of Utah (US)
- Huntsman Cancer Institute (US)
Publication Details
- Journal
- medRxiv
- Published
- 2025-12-19
- DOI
- https://doi.org/10.64898/2025.12.17.25342501
- Primary Topic
- Chromosomal and Genetic Variations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Southern California
- Huntsman Cancer Foundation
- Huntsman Cancer Institute
- National Institutes of Health
- National Center for Research Resources
- National Center for Advancing Translational Sciences