Characterization of chromosome 5 aberrations in <i>TP53</i> mutated myeloid neoplasms with ≥5% blasts: An International <i>TP53</i> Investigators Network (iTiN) study

These findings emphasize the independent prognostic relevance of chromosome 5/5q losses underscoring the clinical relevance of cytogenetic testing for -5/5q even in this high-risk cohort.

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Publication Details

Journal
Cancer
Published
2025-12-19
DOI
https://doi.org/10.1002/cncr.70210
Primary Topic
Acute Myeloid Leukemia Research
Type
article
Field-Weighted Citation Impact
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article

Characterization of chromosome 5 aberrations in TP53 mutated myeloid neoplasms with ≥5% blasts: An International TP53 Investigators Network (iTiN) study

Payal Sojitra, Sharmila Ghosh, Ayalew Tefferi, Hong Chang et al.
Cancer
Acute Myeloid Leukemia Research
article

Characterization of chromosome 5 aberrations in TP53 mutated myeloid neoplasms with ≥5% blasts: An International TP53 Investigators Network (iTiN) study

Payal Sojitra, Sharmila Ghosh, Ayalew Tefferi, Hong Chang, Kedar Inamdar, Anamarija M. Perry, David Andrew Sallman, Anand Patel, Danica Wiredja, Amandeep Kaur, Girish Venkataraman, Jeremy Segal, Madhavi Pandiri, Angela M. Lager, Peng Wang, Claudia Haferlach, Zenggang Pan, Hamza Tariq, Melissa Yuwono Tjota, Daniel A. Arber, Emily Ferguson Mason, Nathanael G. Bailey, Talha Badar, Anna Stengel, Jingjing Zhang, Haipeng Shao, Pranav Pramod Patwardhan, Irfan Yasin
article en

Abstract

These findings emphasize the independent prognostic relevance of chromosome 5/5q losses underscoring the clinical relevance of cytogenetic testing for -5/5q even in this high-risk cohort.

CancerVol. 132(1)
Mayo Clinic (US), NorthShore University HealthSystem (US), Henry Ford Health System (US), University of Toronto (CA), University of Michigan (US), Jacksonville College (US), Johnson University (US), Moffitt Cancer Center (US), University of Chicago (US), Northwestern Memorial Hospital (US), Munich Leukemia Laboratory (Germany) (DE), Children's Hospital Colorado (US), Mayo Clinic in Arizona (US), University of Pittsburgh Medical Center (US), Mayo Clinic in Florida (US), University of Colorado Anschutz Medical Campus (US), Vanderbilt University Medical Center (US), University of Colorado Denver (US)
Openalex Percentile: Top 39%
Acute Myeloid Leukemia Research
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