Exploring the mechanism by which puerarin inhibits neuroinflammation and alleviates lipopolysaccharide-induced anxiety-like behavior in mice via modulating gut microbiota based on the brain-gut axis theory

Puerarin alleviated LPS-induced ALB in mice by suppressing neuroinflammation, restoring intestinal barrier integrity, and modulating GM balance, which was closely associated with GBA regulation.

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Publication Details

Journal
Brain Research Bulletin
Published
2025-12-19
DOI
https://doi.org/10.1016/j.brainresbull.2025.111698
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.00
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article

Exploring the mechanism by which puerarin inhibits neuroinflammation and alleviates lipopolysaccharide-induced anxiety-like behavior in mice via modulating gut microbiota based on the brain-gut axis theory

Dan Wang, Ge Wang, Qisheng Tang
Brain Research Bulletin
Gut microbiota and health
article

Exploring the mechanism by which puerarin inhibits neuroinflammation and alleviates lipopolysaccharide-induced anxiety-like behavior in mice via modulating gut microbiota based on the brain-gut axis theory

Dan Wang, Ge Wang, Qisheng Tang
article en

Abstract

Puerarin alleviated LPS-induced ALB in mice by suppressing neuroinflammation, restoring intestinal barrier integrity, and modulating GM balance, which was closely associated with GBA regulation.

Brain Research BulletinVol. 235
Beijing University of Chinese Medicine (CN)
Openalex Percentile: Top 62%
Gut microbiota and health
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