T3 enhances neuronal activity in an induced pluripotent stem cell derived model of early human brain development
Our results indicate that T3 regulates multiple features of neuronal activity in NGN2-differentiated neurons, illustrating its potential to study normal and disordered thyroid hormone signaling in a human model for early brain development.
Authors
- Ulgu Arslan (ORCID: https://orcid.org/0000-0002-8230-6411)
- Anna López Martí (ORCID: https://orcid.org/0009-0002-3183-9717)
- Cristina Gontan (ORCID: https://orcid.org/0000-0002-3918-0024)
- W. Edward Visser (ORCID: https://orcid.org/0000-0002-5248-863X)
- Dursun Gündüz
- Joris A. van Dongen (ORCID: https://orcid.org/0000-0002-4366-0653)
- Lisa Bauer (ORCID: https://orcid.org/0000-0002-6589-6712)
Institutions
- Erasmus MC (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- European Thyroid Journal
- Published
- 2025-12-18
- DOI
- https://doi.org/10.1530/etj-25-0193
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 0.00