Systemic inflammation indices and serum squamous cell carcinoma (SCC) antigen: an exploratory analysis on prognosis of patients with vulvar squamous cell carcinoma
Elevated SCC-Ag levels in VSCC are associated with lymphopenia and poor tumor differentiation, reflecting an unfavorable systemic immune profile. The combination of SCC-Ag and inflammatory indices, particularly NLR, may offer a simple and cost-effective tool for postoperative prognostic assessment and surveillance planning.
Authors
- Luigi Della Corte (ORCID: https://orcid.org/0000-0002-0584-2181)
- Dominga Boccia (ORCID: https://orcid.org/0009-0008-4151-9470)
- Daniela Terracciano (ORCID: https://orcid.org/0000-0003-4296-429X)
- Mario Palumbo (ORCID: https://orcid.org/0000-0002-0670-2666)
- Giuseppe Bifulco (ORCID: https://orcid.org/0000-0001-7772-8591)
- A. Pollio
Institutions
- Federico II University Hospital (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Gynecologic Oncology Reports
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1016/j.gore.2025.102012
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00