Survival improvement with sirolimus plus tacrolimus immunosuppression for treatment of bronchiolitis obliterans syndrome after lung transplantation
Sirolimus + tacrolimus immunosuppression may improve survival in BOS patients, especially severely affected patients with BOS Grade 3, or rapidly declining or low FEV<sub>1</sub>. Adding MMF or azathioprine to this combination may further increase short-term survival.
Authors
- Si M. Pham (ORCID: https://orcid.org/0000-0001-7396-8344)
- Aldo Iacono (ORCID: https://orcid.org/0000-0001-8967-6290)
- Marniker Wijesinha (ORCID: https://orcid.org/0000-0002-6609-8456)
- Michael L. Terrin (ORCID: https://orcid.org/0000-0002-6342-2900)
Institutions
- University of Maryland, Baltimore (US)
- North Shore University Hospital (US)
Publication Details
- Journal
- JHLT Open
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1016/j.jhlto.2025.100469
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Northwell Health
- National Institutes of Health