Effect of Positive End-Expiratory Pressure on Cardiac Index and Right Ventricular Performance in Ventilated Children Post-Cardiac Surgery

In children with CHD who underwent biventricular repair, cardiac index, RV function, and Cstat generally improved with higher PEEP, indicating pulmonary recruitment. Changes in cardiac performance and Cstat were closely related, with both improving or worsening together with manipulation of PEEP. This study supports the use of PEEP to optimize lung volume and cardiopulmonary interactions after cardiac surgery.

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Publication Details

Journal
Pediatric Critical Care Medicine
Published
2025-12-19
DOI
https://doi.org/10.1097/pcc.0000000000003880
Primary Topic
Respiratory Support and Mechanisms
Type
article
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article

Effect of Positive End-Expiratory Pressure on Cardiac Index and Right Ventricular Performance in Ventilated Children Post-Cardiac Surgery

Jan-Christoph Clausen, Oliver Miera, Michael Emeis, Martin C. J. Kneyber et al.
Pediatric Critical Care Medicine
Respiratory Support and Mechanisms
article

Effect of Positive End-Expiratory Pressure on Cardiac Index and Right Ventricular Performance in Ventilated Children Post-Cardiac Surgery

Jan-Christoph Clausen, Oliver Miera, Michael Emeis, Martin C. J. Kneyber, Joachim Photiadis, Tania Garfias‐Veitl, Maren Kleine‐Brueggeney, Richard Hollander, Robert G. T. Blokpoel, Thomas Asendorf, Felix Berger, Vasile-Valentin Vadiunec
article en

Abstract

In children with CHD who underwent biventricular repair, cardiac index, RV function, and Cstat generally improved with higher PEEP, indicating pulmonary recruitment. Changes in cardiac performance and Cstat were closely related, with both improving or worsening together with manipulation of PEEP. This study supports the use of PEEP to optimize lung volume and cardiopulmonary interactions after cardiac surgery.

Pediatric Critical Care MedicineVol. 27(2)
University Medical Center Groningen (NL), University of Groningen (NL), Humboldt-Universität zu Berlin (DE), Universitätsmedizin Göttingen (DE), Deutsches Herzzentrum München (DE), Freie Universität Berlin (DE), Charité - Universitätsmedizin Berlin (DE)
Openalex Percentile: Top 40%
Respiratory Support and Mechanisms
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