Incidence, Predictors, and Outcomes of Major Transcatheter Aortic Valve Replacement (TAVR) Complications and Failure-to-Rescue in the Contemporary Era
While the proportion of TAVR patients experiencing surgical emergencies has remained stable over time, the overall prevalence is increasing with the growth of TAVR, and these complications are associated with an in-hospital mortality rate of greater than 25%. Younger age, female sex, bicuspid valve, and thoracic aneurysm are associated with increased risk of major complications.
Authors
- Nimesh D. Desai (ORCID: https://orcid.org/0000-0002-4456-5674)
- Ashwin S. Nathan (ORCID: https://orcid.org/0000-0002-7227-6423)
- Alexandra Sperry (ORCID: https://orcid.org/0000-0003-1741-7147)
- Lauren Gillinov (ORCID: https://orcid.org/0000-0002-1720-3504)
- Nicholas Goel (ORCID: https://orcid.org/0000-0001-8210-5815)
- Omar Toubat (ORCID: https://orcid.org/0000-0002-3377-1384)
- Kendall M. Lawrence (ORCID: https://orcid.org/0000-0002-2698-5720)
- Michael A. Catalano (ORCID: https://orcid.org/0000-0001-8656-6352)
- Daniel Bazianos
- Chase R. Brown (ORCID: https://orcid.org/0000-0002-3956-0406)
- Wilson Y. Szeto
Institutions
- University City Science Center (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Interdisciplinary CardioVascular and Thoracic Surgery
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1093/icvts/ivaf311
- Primary Topic
- Cardiac Valve Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- University of Pennsylvania
- Agency for Healthcare Research and Quality