Germline Predisposition to Oncogenic Alkylating Damage in Colorectal Cancer
Our results support a causal relationship between red meat and colorectal cancer and may inform tailored dietary and screening guidelines for colorectal cancer prevention.
Authors
- Tomotaka Ugai (ORCID: https://orcid.org/0000-0003-0182-5269)
- Jeffrey A. Meyerhardt (ORCID: https://orcid.org/0000-0002-1120-0898)
- Chichun Tan (ORCID: https://orcid.org/0000-0001-9310-1991)
- Edward L. Giovannucci (ORCID: https://orcid.org/0000-0002-6123-0219)
- Matan Hofree (ORCID: https://orcid.org/0000-0001-8368-0299)
- Carino Gurjao (ORCID: https://orcid.org/0000-0002-4813-5460)
- Marios Giannakis (ORCID: https://orcid.org/0000-0001-9012-6982)
- Jonathan Andrew Nowak (ORCID: https://orcid.org/0000-0002-0943-7407)
- Brendan Reardon (ORCID: https://orcid.org/0000-0002-1716-5720)
- Shuji Ogino (ORCID: https://orcid.org/0000-0002-3909-2323)
- Jeffrey P. Townsend (ORCID: https://orcid.org/0000-0002-9890-3907)
- Jules Cazaubiel (ORCID: https://orcid.org/0009-0007-1992-3197)
Institutions
- Broad Institute (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- John Brown University (US)
- Harvard University Press (US)
- Yale Cancer Center (US)
- Yale University (US)
- University of Massachusetts Boston (US)
- Institute for Research in Immunology and Cancer (CA)
- Dana-Farber Cancer Institute (US)
- Yale New Haven Health System (US)
- Dana-Farber/Harvard Cancer Center (US)
- Université de Montréal (CA)
Publication Details
- Journal
- Cancer Epidemiology Biomarkers & Prevention
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1158/1055-9965.epi-25-1006
- Primary Topic
- Nutritional Studies and Diet
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancer Research UK
- National Institutes of Health
- Centers for Disease Control and Prevention
- National Cancer Institute
- Janssen Pharmaceuticals