Exercise therapy for gestational diabetes mellitus: from basic to clinical

This article reviews exercise therapy for gestational diabetes mellitus (GDM). First, the pathophysiological basis of GDM was described, including epidemiological characteristics, pathological mechanisms, and progress in diagnostic techniques. The basic theory of exercise therapy is discussed, including the effect of exercise on the pathophysiology of GDM, the biological mechanism, and the comparison of the curative effect of different forms of exercise. This was followed by an in-depth analysis of clinical exercise therapy practices including exercise prescription formulation, clinical trial analysis, and safety assessment. Simultaneously, the technical progress of exercise therapy is introduced, including the application of exercise monitoring technology and digital health tools, as well as the development and application of personalized exercise therapy programs. In addition, the controversies and challenges of exercise therapy, such as indications and contraindications, compliance issues, and long-term efficacy evaluations, are discussed. Finally, the research trend, the potential of innovative exercise therapy, and the prospect of multidisciplinary cooperation are discussed to provide a comprehensive and in-depth theoretical and practical reference for exercise therapy for GDM.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-12-19
DOI
https://doi.org/10.3389/fmed.2025.1716883
Primary Topic
Gestational Diabetes Research and Management
Type
article
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article

Exercise therapy for gestational diabetes mellitus: from basic to clinical

Lin Zhang, Xiaying Niu, Li Li, Kaiwen Wang
Frontiers in Medicine
Gestational Diabetes Research and Management
article

Exercise therapy for gestational diabetes mellitus: from basic to clinical

Lin Zhang, Xiaying Niu, Li Li, Kaiwen Wang
article en

Abstract

This article reviews exercise therapy for gestational diabetes mellitus (GDM). First, the pathophysiological basis of GDM was described, including epidemiological characteristics, pathological mechanisms, and progress in diagnostic techniques. The basic theory of exercise therapy is discussed, including the effect of exercise on the pathophysiology of GDM, the biological mechanism, and the comparison of the curative effect of different forms of exercise. This was followed by an in-depth analysis of clinical exercise therapy practices including exercise prescription formulation, clinical trial analysis, and safety assessment. Simultaneously, the technical progress of exercise therapy is introduced, including the application of exercise monitoring technology and digital health tools, as well as the development and application of personalized exercise therapy programs. In addition, the controversies and challenges of exercise therapy, such as indications and contraindications, compliance issues, and long-term efficacy evaluations, are discussed. Finally, the research trend, the potential of innovative exercise therapy, and the prospect of multidisciplinary cooperation are discussed to provide a comprehensive and in-depth theoretical and practical reference for exercise therapy for GDM.

Frontiers in MedicineVol. 12
Beijing Obstetrics and Gynecology Hospital (CN)
Openalex Percentile: Top 48%
Gestational Diabetes Research and Management
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Exercise therapy for gestational diabetes mellitus: from basic to clinical — Lin Zhang, Xiaying Niu, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS