Dynamic Inner Blood Retina Barrier Disruption in Retinitis Pigmentosa
Cumulatively, these findings represent the first quantitative profiling of iBRB disruption in RP and suggest that retinal vascular stabilization may represent a gene agnostic approach to treating this devastating form of blindness.
Authors
- Emma Duignan (ORCID: https://orcid.org/0000-0002-3968-4855)
- Jeffrey O’Callaghan (ORCID: https://orcid.org/0000-0001-8818-4331)
- Matthew E. Campbell (ORCID: https://orcid.org/0000-0003-3325-240X)
- Paul F. Kenna (ORCID: https://orcid.org/0000-0002-3964-4167)
- Conor P. Delaney (ORCID: https://orcid.org/0000-0001-8735-2225)
- Kevin P. Byrne (ORCID: https://orcid.org/0000-0002-6368-154X)
- Kieva Byrne
- Natalie Hudson (ORCID: https://orcid.org/0000-0001-9163-8779)
- Sarah Doyle (ORCID: https://orcid.org/0000-0002-6294-9380)
- Nicole Hanley (ORCID: https://orcid.org/0000-0003-1451-3803)
- Rory Holohan
- Mark Cahill
- Peter Humphries
- Marian M. Humphries
- Denis Nevrov
Institutions
- Trinity College Dublin (IE)
- Royal Victoria Eye and Ear Hospital (IE)
- Progress (Ireland) (IE)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1167/iovs.66.15.61
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Science Foundation Ireland
- Irish Research Council