Upregulation of lncRNA CASC2 alleviates neuroinflammation in acute ischemic stroke and exhibits protective effects by targeting miR-155 (CASC2 role in AIS)
CASC2 exerts a protective effect in AIS by sponging miR-155, thereby attenuating neuroinflammation and ameliorating clinical outcomes. CASC2 and miR-155 may serve as valuable prognostic biomarkers in AIS patients.
Authors
- Qiaodan Hu (ORCID: https://orcid.org/0000-0001-7639-9239)
- Yuhao Zhang (ORCID: https://orcid.org/0000-0001-9081-3125)
- Zhiyu Wang (ORCID: https://orcid.org/0000-0002-9502-9329)
- Chenting Jin
Institutions
- Xuzhou Medical College (CN)
- Dalian Medical University (CN)
- Third Affiliated Hospital of Southern Medical University (CN)
- Nanjing Traditional Chinese Medicine Hospital (CN)
- Second Affiliated Hospital of Dalian Medical University (CN)
- Second People’s Hospital of Huai’an (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1186/s40001-025-03391-9
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00