A Solitary Giant Neurofibroma of the Left Chest

This article presents a case of a 29-year-old female patient with a giant neurofibroma in the left chest area, weighing 7 kg and accounting for 28% of her body weight. Numerous patients with neurofibromatosis remain undiagnosed or fail to receive optimal treatment because they are asymptomatic or experience late-onset symptoms. Surgical resection serves as the principal treatment for giant neurofibromas. Nevertheless, it is a formidable challenge owing to tumor infiltration and extensive vascularity, which poses a risk of severe hemorrhage. In this case, by implementing ancillary procedures like ligating the feeding and nutrient arteries, the tumor was successfully excised with minimal blood loss. After the operation, the patient was discharged 20 days later and regained the ability to walk independently.

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Publication Details

Journal
Journal of Craniofacial Surgery
Published
2025-12-19
DOI
https://doi.org/10.1097/scs.0000000000012275
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
Field-Weighted Citation Impact
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article

A Solitary Giant Neurofibroma of the Left Chest

Xiang You, Wei Cui, Zhen Cai, Maohua Chen
Journal of Craniofacial Surgery
Neurofibromatosis and Schwannoma Cases
article

A Solitary Giant Neurofibroma of the Left Chest

Xiang You, Wei Cui, Zhen Cai, Maohua Chen
article en

Abstract

This article presents a case of a 29-year-old female patient with a giant neurofibroma in the left chest area, weighing 7 kg and accounting for 28% of her body weight. Numerous patients with neurofibromatosis remain undiagnosed or fail to receive optimal treatment because they are asymptomatic or experience late-onset symptoms. Surgical resection serves as the principal treatment for giant neurofibromas. Nevertheless, it is a formidable challenge owing to tumor infiltration and extensive vascularity, which poses a risk of severe hemorrhage. In this case, by implementing ancillary procedures like ligating the feeding and nutrient arteries, the tumor was successfully excised with minimal blood loss. After the operation, the patient was discharged 20 days later and regained the ability to walk independently.

Journal of Craniofacial SurgeryVol. 37(3/4)
University of Electronic Science and Technology of China (CN), Sichuan University (CN), West China Hospital of Sichuan University (CN), Health and Family Planning Commission of Sichuan Province (CN)
Openalex Percentile: Top 44%
Neurofibromatosis and Schwannoma Cases
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