Fine‐needle aspiration cytology reduces the frequency of surgeries for malignant salivary gland tumors
The use of the MSRSGC enables reliable preoperative risk stratification of malignant salivary gland tumors. High-to-intermediate-risk categories (Milan III/IVb/V/VI) were associated with a lower likelihood of multiple surgeries. True-positive FNAC results were most frequent in squamous cell carcinoma and metastatic melanoma, whereas acinic cell, mucoepidermoid, and salivary duct carcinomas were prone to misclassification. Structured FNAC reporting improves diagnostic accuracy and informs personalized surgical planning, reducing interventions and optimizing management.
Authors
- Lisa Nachtsheim (ORCID: https://orcid.org/0000-0002-0261-4511)
- Marcel Mayer (ORCID: https://orcid.org/0000-0001-9963-1109)
- Louis Jansen (ORCID: https://orcid.org/0000-0003-0332-1099)
- Sami Shabli (ORCID: https://orcid.org/0000-0002-7202-0460)
- Christoph Arolt (ORCID: https://orcid.org/0000-0002-6366-2285)
- Lena Hieggelke (ORCID: https://orcid.org/0000-0002-1831-0387)
- Alexander Quaas (ORCID: https://orcid.org/0000-0002-3537-6011)
- Hans Nikolaus Caspar Eckel (ORCID: https://orcid.org/0000-0002-6947-9836)
- Julia Eßer (ORCID: https://orcid.org/0009-0002-3556-3738)
- Kathrin Möllenhoff (ORCID: https://orcid.org/0000-0001-7861-3892)
- Jens Peter Klußmann (ORCID: https://orcid.org/0000-0002-8223-7954)
- Philipp Wolber (ORCID: https://orcid.org/0000-0001-9019-2840)
- Kevin Hansen (ORCID: https://orcid.org/0000-0001-5028-0600)
- Marianne Engels
- Sofia Kourou (ORCID: https://orcid.org/0009-0000-2277-4160)
- Marwan Alfarra
- Charlotte Laatz
Institutions
- University of Cologne (DE)
Publication Details
- Journal
- Cancer Cytopathology
- Published
- 2025-12-19
- DOI
- https://doi.org/10.1002/cncy.70070
- Primary Topic
- Salivary Gland Tumors Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00